2007-2008 CAFA Faculty Development Grants

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The Robert T. Poe Faculty Development Grant

Yadong Yin -- Shape Control of Nanocrystals by Wet Chemical Etching

Professor Yadong Yin is an Assistant Professor at the Department of Chemistry, University of California, Riverside. This project aims to develop a wet chemical etching method to control the shape of nanocrystalline materials. Uniform spherical nanocrystals will be first synthesized using existing methods, and then chemically etched to form new shapes as the result of different etching rates on different crystal facets. New physical properties (e.g. optical, magnetic and electronic properties) will emerge along with the novel geometric shapes. This proposal asks for funds to help generating preliminary results for a full grant application. Dr. Yin was a staff scientist at the Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, before he arrived in UCR in 2006.

The CAFA Faculty Development Grant

Jun Wu -- Establish Novel Multiple Myeloma Orthotopic Xenograft Model for Preclinical Studies

Dr. Jun Wu is an Assistant Research Scientist at the City of Hope Comprehensive Cancer Center. The proposal asks for funding to purchase materials and supplies for this research. Multiple myeloma (MM) is currently an incurable B cell malignancy that accounts for 10% of human hematopoietic malignancies. The delay in therapeutic development for MM is mainly because of the lack of suitable animal model of MM that can faithfully recapitulate the nature characters of the disease in vivo for better understanding the molecular and cellular mechanism, and pre-clinical assessment of novel chemotherapy. This project involves the development of an animal model that will provide novel humanized bone marrow microenvironment for the growth ofxenografted primary human MM cells, and a noninvasive monitoring opportunity to observe the sequential initiation, progression, metastasis events and drug response of the natural development of MM. Dr. Wu was a research fellow at the University of Southern California before he became a member of the City of Hope in 2007.

Shinyi Wu -- Coaching Healthcare Providers for Improving Chronic Care and Business Strategies in the Safety Net

Professor Shinyi Wu is an Assistant Professor at the Daniel J. Epstein Department of Industrial and Systems Engineering, University of Southern California. This proposal asked for funding to purchase the software and literature review on coaching interventions, supporting the project funded by the Agency for Healthcare Research and Quality (AHRQ). Dr. Wu's research will develop, test, and disseminate a toolkit and practice coaching strategy to help safety-net practices implement the Chronic Care Model in a sustainable, efficient way. Dr. Wu arrived at USC in January 2008. Prior to joining USC, she was a researcher in the RAND Corporation's Health Program and Technology & Applied Sciences Group.

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